Andrew (Italian Andrea) Franchi was born in 1335 at Pistoia to the Boccagnini family. He entered the Dominican Order at Pistoia and rose through the Dominican governance offices — prior of Orvieto, Lucca, and Pistoia.
In 1381, Andrew was appointed Bishop of Pistoia by Pope Urban VI (Roman-obedience pope during the Great Western Schism). His twenty-year episcopate (1381–1401) was devoted to the systematic Catholic pastoral reform of the Tuscan diocese under the specifically Dominican pattern of the Observant Reform.
Andrew famously distributed his episcopal revenues to the Pistoian poor and maintained the personal poverty despite his episcopal office. He died at Pistoia on May 26, 1401.

