Diego Laynez (also spelled Laínez, Latin Iacobus Laynez) was born in 1512 at Almazán in Castile to a converso Jewish family — descendant of Spanish Jews who had converted to Catholicism under the 1492 Alhambra Decree of King Ferdinand and Queen Isabella.
Educated at the University of Alcalá (Jesuit-friendly Spanish Catholic humanist university) and the University of Paris, Diego met Ignatius Loyola at Paris around 1533 and became one of the Seven Original Companions who took the Montmartre Vows on August 15, 1534 — an institutional co-founder of the Society of Jesus.
Diego served at the Council of Trent as papal theologian — one of the two Jesuit theologians (with Alfonso Salmerón) present at all three sessions of the Council (1545–1547, 1551–1552, 1562–1563). His theological contributions at Trent shaped key Tridentine doctrinal definitions — most famously the Decree on Justification of the Sixth Session (January 13, 1547).
Upon the death of Ignatius Loyola on July 31, 1556, Diego was elected second Superior General of the Society of Jesus at the General Congregation of 1558. His seven-year tenure (1558–1565) consolidated the Ignatian institutional structure and supervised the rapid Jesuit expansion.
He died at Rome on January 19, 1565 while the Council of Trent's third session was in its final phase.

