Guadalupe Ortiz de Landázuri Fernández de Heredia was born on December 12, 1916 at Madrid. Educated at the Central University of Madrid, Guadalupe received the degree in chemistry in 1941 — becoming one of the first Spanish women to receive the chemistry doctorate.
In 1944, Guadalupe met St. Josemaría Escrivá and joined the Opus Dei — becoming the first female Opus Dei Numerary in Madrid.
In 1950, Guadalupe was sent to Mexico to establish the first Opus Dei women's community outside Europe — in the women's-vocation apostolate.
For 5 years (1950–1956), Guadalupe led the Mexican Opus Dei women's community.
In 1965, Guadalupe received the chemistry doctorate at the University of Madrid — on the research on insulation materials for the Spanish rural households.
She died at Pamplona on July 16, 1975 at the age of 58 — 20 days after the death of St. Josemaría Escrivá.
Beatified May 18, 2019 by Pope Francis — the first female Opus Dei Numerary beatified.