Jakob Griesinger was born in 1407 at Ulm in the Duchy of Württemberg. Trained as a stained-glass artist in the German-Ulm workshops, he travelled to Italy in his youth as an itinerant journeyman-artist.
Around 1441, at the age of 34, James entered the Dominican Order at the Basilica of San Domenico at Bologna — the Dominican mother-house of the Order (containing the tomb of St. Dominic himself) — as a lay-brother (the Dominican non-priestly religious-brother status).
James continued to practise the stained-glass artistic vocation as a Dominican lay-brother — executing the famous stained-glass windows for the Basilica of San Petronio at Bologna (completed 1465–1470), the San Domenico stained-glass windows, and multiple additional Bolognese and Ferrarese ecclesiastical stained-glass commissions.
His artistic style — combining the late-Gothic German-Ulm stained-glass tradition with the Early Renaissance Italian iconographic-perspectival innovations — establishes the late-15th-century Italian stained-glass tradition.
James lived at the Bolognese Dominican convent for 50 years — famously combining the lay-brother religious discipline with the continuing artistic vocation. He died at Bologna on October 11, 1491 at the age of 84.

