Werburgh (Old English Wǣrburh) was a daughter of King Wulfhere of Mercia and St. Ermenilda, granddaughter of St. Sexburga of Ely, and great-granddaughter of King Anna of East Anglia — placing her in the most extensive 7th-century English royal-saint dynasty.
Refusing the marriage proposal of Werbod, a Mercian noble, she took the veil at Ely under her great-aunt St. Etheldreda. After Wulfhere's death in 675, her uncle King Æthelred of Mercia appointed her supervising abbess over all the women's monasteries of Mercia — a unique appointment combining royal patronage with monastic governance.
She founded or reformed the convents of Trentham, Hanbury, and Weedon, and died at Trentham around 700. Her body was translated to Hanbury per her own request, and remained there until 875 when, threatened by Danish raids, her remains were taken to the safer walled town of Chester, where the Anglo-Saxon minster (later the great Norman Benedictine abbey, today's Anglican Chester Cathedral) became her permanent shrine.

