Around 1400 in the Dutch town of Boxmeer, a parish priest celebrating Mass and tormented by doubts about the Real Presence saw, at the moment of consecration, the wine in his chalice transform into blood and rise above the rim. The bloodied corporal was preserved. The bishop of Liège (whose diocese then included Boxmeer) confirmed the cult.
The relic is venerated at the Basilica of St. Peter at Boxmeer. The Heilig Bloed Processie (Holy Blood Procession) on the Sunday after the feast of the Sacred Heart — held continuously for over 600 years — is one of the great living Dutch Eucharistic processions.