PREPARATORY PRAYER (for each day, and for the novena to any one of them)
Almighty and eternal God! With lively faith and reverently worshipping Thy divine Majesty, I prostrate myself before Thee and invoke with filial trust Thy supreme bounty and mercy. Illumine the darkness of my intellect with a ray of Thy heavenly light and inflame my heart with the fire of Thy divine love, that I may contemplate the great virtues and merits of the saint in whose honour I make this novena, and following his example imitate, like him, the life of Thy divine Son.

Moreover, I beseech Thee to grant graciously, through the merits and intercession of this powerful Helper, the petition which through him I humbly place before Thee, devoutly saying, 'Thy will be done on earth as it is in heaven.' Vouchsafe graciously to hear it, if it redounds to Thy greater glory and to the salvation of my soul. Amen.

PRAYER (each day)
My Lord and my God! I offer up to Thee my petition in union with the bitter passion and death of Jesus Christ, Thy Son, together with the merits of His immaculate and blessed Mother, Mary ever virgin, and of all the saints, particularly with those of the holy Helper in whose honour I make this novena.

Look down upon me, merciful Lord! Grant me Thy grace and Thy love, and graciously hear my prayer. Amen.

CONCLUDING PRAYER (on the ninth day)
O faithful servants of God and powerful protectors of man, Holy Helpers! Since our Lord appointed you the heavenly advocates for our needs on earth, I confidently turn to you for help in my distress. Countless numbers praise you for aiding them with counsel in doubt, with consolation in anxiety, with health in illness, with safety in danger, with delivery from prison, and with help and assistance in all tribulations. Therefore I, too, have recourse to you, and implore you not to refuse me your aid.

Give thanks to God for me for all the graces He granted me during this novena. I ascribe them to your great merits and powerful intercession. I thank you all together, and each one in particular, for your interest in my favour before the throne of God. I commend myself to your continued protection, that I may one day be united with you in heaven. Amen.

St. George, martyr — for soldiers, and for the health of domestic animals.
St. Blaise, bishop and martyr — against diseases of the throat.
St. Erasmus (Elmo), bishop and martyr — for sailors, and against abdominal pain.
St. Pantaleon, physician and martyr — for physicians, and for the sick.
St. Vitus, martyr — against epilepsy and nervous disorders.
St. Christopher, martyr — for travellers, and against sudden death.
St. Denis (Dionysius), bishop and martyr — against headache, and for France.
St. Cyriacus, deacon and martyr — against temptation, especially at the hour of death.
St. Acacius (Achatius), martyr — against headache and in the agony of death.
St. Eustace, martyr — for hunters, and in family difficulties.
St. Giles, hermit and abbot — for the disabled and the poor, and for a good confession.
St. Margaret of Antioch, virgin and martyr — for women in childbirth.
St. Catherine of Alexandria, virgin and martyr — for students, philosophers and a good death.
St. Barbara, virgin and martyr — against sudden and unprovided death, and for the last sacraments.